This study also identified Homologous to the C‐terminus of E6AP and RCC1‐like domain‐containing E3 ubiquitin protein ligase 5 (HERC5) as an E3 ligase that targets 4EBP1 for degradation, which could be prevented by GS in NSCLC.47 This evidence concerns the gene HERC5 and non-small cell lung carcinoma.