In the other hand, while an association was observed between D2T axSpA and arthritis (P = 0.02), as well as activity scores before initiating first biologic (BASDAI (P = 0.04), ASDAS CRP (P = 0.03)) in univariate regression analysis, this association did not remain statistically significant in multivariate analysis. The gene discussed is CRP; the disease is arthritic joint disease.