Genome-wide association studies identified the risk loci for ischemic stroke and its subtypes related to atrial fibrillation (PITX 2 and ZFHX 3), coronary artery disease (ABO, chr9p21, HDAC 9 and ALDH 2), blood pressure (HLDH 2 and HDAC 9), pericyte and smooth muscle cell development (FOXF 2), coagulation (HABP2), carotid plaque formation (MMP 12), and neuroinflammation (TSPAN2) (10). Here, HABP2 is linked to ischemic stroke.