GFRA1 and cancer: Regarding potential subclinical infections, it is notable that several of the proteins linked to low wellbeing are involved in hepatis virus infection (KIM1, ASGR1) and replication (AMBP, MSR1) as well as other liver-related processes such as hepatic inflammation, cancer, and alcohol-related liver disease (EDA2R, GFRA1, UNC5C, TNFRSF10A, TNFRSF11A).