DEFB4A and infection: DEFB4A belongs to the defensin family, a group of cytotoxic peptides secreted by neutrophils that play crucial roles in the innate immune defense against microbial infections.[20, 22] By enhancing the body’s defense against infections and regulating inflammation, DEFB4A may help maintain a balanced immune response, potentially reducing chronic inflammation.[20] Through its antimicrobial and anti-inflammatory properties, DEFB4A may contribute to overall health and positive wellbeing.