The CpG site cg13422045, assigned to ARHGEF17, also showed similar associations across three CSF AD biomarkers (tTau, pTau and pTau+/−), with the strongest associations observed for pTau (effect estimate: −0.010, p-value: 2.76e-06) and pTau+/− (effect estimate: −0.003, p-value: 8.23e-06; Figure 1F). The gene discussed is ARHGEF17; the disease is Alzheimer disease.