stated that H. aspersa slime inhibits the growth of IGR‐39 and SK‐MEL‐28 melanoma cells, by increasing expression of the cytokine Tumor Necrosis Factor (TNF‐α), and inhibits the transcription process, by blocking transcription nuclear factor kappa activated B cells (NF‐κB), that in proper regulation has been linked to cancer progression [2]. This evidence concerns the gene TNF and melanoma.