All the inflammatory cytokines and chemokines including IL-6, IL-1β, IL-4, IL-5, IL-10, IL-13, IFN-γ, TNF-α, GM-CSF, monocyte chemoattractant protein-1 (MCP-1), and macrophage inflammatory protein-1β (MIP-1β) were upregulated in both DF and DHF patients [29]. This evidence concerns the gene TNF and dengue disease.