To identify the downstream effectors of MIR181A1HG in CRC cell-derived EVs that are involved in CRLM, Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed on the genes differentially expressed between high and low MIR181A1HG-expressing CRC tumors from TCGA data. Here, MIR181A1HG is linked to colorectal carcinoma.