MIR181A1HG and colorectal carcinoma: More interestingly, we further assessed MIR181A1HG expression in the serum EVs of 20 patients with CRLM before radical resection as well as one week after simultaneous resection of primary CRC tumors and LMs and found that the expression level of MIR181A1HG in the serum EVs of the same patient was significantly decreased one week after surgery (Fig. 1g, Supplementary Table S6).