Co-culture of TCRG4.1-transduced CD8+ T cell with an HLA-A2−, NEJGNAS-expressing GBM cell line (Mayo, patient-derived xenograft, GBM39) revealed cytotoxicity only when the gene encoding HLA-A*02:01 was transduced (Fig. 5h). This evidence concerns the gene HLA-A and glioblastoma.