In the primary NSCLC cells, priNSCLC-1, stable transfection of the OE-POPDC3 construct led to robust POPDC3 mRNA and protein upregulation (Fig. 9J), where POPDC1 and POPDC2 mRNA levels were unchanged (Fig. 9K, L). Here, POPDC2 is linked to non-small cell lung carcinoma.