Moreover, to our knowledge, this is the first time that the protein-protein interaction of MEOX2, with GLI-1, SMARCB1, BRD9 and CBP is ever shown, but it has been reported that homeobox proteins (HOXB13) interact with subunits of mSWI/SNF (SMARCC1) in prostate cancer [57], in agreement with our results in lung cancer. The gene discussed is HOXB13; the disease is Familial prostate cancer.