Many of these parameters were found to be significantly (p < 0.01) decreased when also comparing T2 to T0 in this Control->FMD: leptin, serum glucose, insulin, total cholesterol, LDL, AST, ALT and uremia, HOMA-IR, as well as WC, BMI, estimated FM (in both % and kg), and VF levels, whereas a significant (p < 0.01) increase in ghrelin, HOMA %S, and estimated MM (in both % and kg) was found. The gene discussed is GHRL; the disease is uremia.