A complex consisting of copper (II) benzene-1,3,5-tricarboxylate as a carrier for DDTC (Cu-BTC@DDTC) significantly reduces the viability, migration capacity, and invasiveness of melanoma cells while inducing ferroptosis via the inhibition of solute carrier family 7 member 11 (SLC7A11)/glutathione peroxidase 4 (GPX4) signaling [81]. This evidence concerns the gene GPX4 and melanoma.