IL1B and ischemic stroke: Additionally, a study in an experimental ischemic stroke mouse model demonstrated that intraperitoneal injection of resolvin D2 nanoparticles, a derivative of docosahexaenoic acid (DHA) with anti-inflammatory properties, reduced inflammatory cytokines such as TNF-α, IL-6, and IL-1β, leading to a decrease in brain damage volume from 46% in the control group to 16% in the treated group [112].