CRP and infection: CRP has been increasingly suggested as an acute inflammatory protein with a critical effect on infection responses and inflammatory processes in the host, such as apoptosis, the complement pathway, phagocytosis, nitric oxide production, and cytokine generation, especially TNF-α and IL-6.[7–11] CRP activates many types of immune cells, including macrophages and dendritic cells, making them more active and involved in the inflammatory process, which helps the body to respond quickly to potential threats.