Resveratrol may help rats with DVT by blocking the HIF-1α/NLRP3 pathway, according to an experimental investigation.[36] Additionally, EGCG and warfarin altered HIF-1α and VEGF to prevent inflammation and rabbit DVT via the PI3K/AKT and ERK1/2 signaling pathways, according to another study.[37] Therefore, we believe that HIF-1α and VEGF are significant as predictive markers of thrombosis in the clinic. This evidence concerns the gene HIF1A and deep vein thrombosis.