SOAT1 and bone fracture: Additionally, using AG490 right after ischemia greatly reduced kidney damage.[31] These studies and the current experiment’s findings led us to hypothesize that the Jak-STAT signaling pathway, which is mediated by the STAT family, is crucial to the development of DVT and that preventing the development of DVT following a hip fracture can be achieved by modifying related targets and pathways (Fig. 7A).