Of all parameters, age, history of allergies, clinical symptoms (including sore throat, hoarseness, wheezing, barking cough, dyspnea, diffuse congestion, swelling of the laryngeal mucosa, vocal cord congestion), laboratory indicators (WBC count, and CRP, TNF-α, IL-4, IL-6, IL-17, and IFN-γ levels) were risk factors for the efficacy of treatment in children with acute laryngitis and laryngeal obstruction (Table 3). The gene discussed is IL4; the disease is acute laryngitis.