Cutaneous T cell lymphoma reveals positive CD2, CD3,CD4,TCR-beta, characteristically lacking CD7, CD8, CD25 and CD30; and usually expressing PD1 by immunohistochemical stain.[5] Immunophenotyping confirms that T-cell origin (CD3+ and CD4+) and lack of expression of CD7, CD30 are supportive of cutaneous T cell lymphoma.The loss of CD26 expression and positivity for KIR3DL2 (CD158k) has a high specificity for SS.[6]. The gene discussed is DPP4; the disease is primary cutaneous T-cell non-Hodgkin lymphoma.