ESR1 and primary ovarian failure: Quercetin exhibits antioxidant, anti-inflammatory, and immunomodulatory effects.[32] Quercetin, a major bioactive component of Danggui Buxue Decoction, has been demonstrated to interact with critical targets like p53, IL-6, and AKT1, consequently ameliorating premature ovarian failure by regulating the estrogen receptor/androgen receptor balance in the TP53-AKT signaling cascade.[33] Additionally, quercetin, a key active component of Yinchenhao Decoction, exhibits novel anti-inflammatory properties.