IL18 and pancreatic intraductal papillary-mucinous neoplasm: This hypothesis is reinforced by the higher levels of caspase‐1, IL‐18, and IL‐1RA observed in MUC1‐positive IPMN cases, which is consistent with the protein expression pattern observed in MUC1‐expressing PDAC, as demonstrated by several studies, including our findings [49, 52, 53].