PGK1 and cancer: Under hypoxic conditions, HIF‐1 induces the expression of several genes involved in glycolysis and the pentose phosphate pathway (PPP) including the upregulation of glucose transporter (GLUT1), the rate‐limiting glycolytic enzyme hexokinase (HKII), glycolytic regulator phosphofructo‐2‐kinase (PFK1), pyruvate kinase (PK), pyruvate dehydrogenase kinase (PDK), lactate dehydrogenase (LDH), and phosphoglycerate kinase 1 (PGK1) promoting cancer cell survival even in oxygen‐deprived environments.