VCP and atherosclerosis: 2024). This study demonstrated that PTGS2 and VCP play important roles in naringenin alleviating radiation-induced cell damage through ferroptosis. Additionally, the significance of PTGS2 has also been identified in various other diseases. Previous studies also supported that PTGS2 is considered as a key gene in influencing the prognosis of cervical cancer (Zou et al. 2022), and its protein product function as a potential therapeutic target for atherosclerosis since PTGS2 served as a hub gene in regulatory networks (Zhou et al. 2021).