Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis indicated that the upregulated differentially expressed genes (DEGs) in GSCs were enriched in retinoic acid‐inducible gene I (RIG‐I)‐like receptors, phosphatidylinositol 3‐kinase (PI3K)‐Akt signaling pathway, and Hippo signaling pathway (Figure 1D), which are related to the growth and self‐renewal of cancer stem cells [17, 18, 19]. This evidence concerns the gene AKT1 and cancer.