Moreover, after multivariable adjustment for preoperative PSA-value, pTstage, Gleason Grade group in RP specimen, pNstage, surgical margin status, and adjuvant radiation therapy, interval from biopsy to RP did not receive independent predictor status for BCR after RP in both intermediate- and high-risk prostate cancer patients (p=0.5 and p=0.9). Here, KLK3 is linked to Familial prostate cancer.