Overlapping features of NF1 (cutaneous neurofibromas and café-au-lait spots since age 7 y) and NF2 (meningiomas, vestibular and spinal schwannomas), and a mediastinal ganglioneuroma (associated with both NF1 and NF2). Died from pneumonia (age 35 y); PitNET found in autopsy. FH unremarkable. The gene discussed is NF2; the disease is meningioma.