Sanger: NF1: c.4600C>T, p.R1534* (ClinVar VCV000220152.71, pathogenic/LP); no LOH in somatotropinoma, parathyroid adenoma, and FTC. Heterozygous somatic GNAS (NM_000516.7): c.601C>T, p.R201C (pathogenic) in somatotropinoma. Negative for germline MEN1 variants, somatic CDKN1B variants in parathyroid adenoma, and somatic PAX8/PPARG rearrangements in FTC. Here, PAX8 is linked to growth hormone-producing pituitary gland neoplasm.