Furthermore, we had originally demonstrated that WD/FG significantly increased mRNA levels of Gal, Galr1, Galr2, and Galr3 in mouse heart ventricles compared to those in negative controls in our experiments, suggesting that other members except for GalR2 might play a role in cardiovascular physiology and pathophysiology related to metabolic diseases. This evidence concerns the gene GALR2 and Other metabolic disease.