WFDC2 and ovarian cancer: Zhu et al. have reported that miR-205 exosomal level is increased in ovarian cancer patients, and combining miR-205 exosomal level with CA-125 and protein HE4 increases the sensitivity and specificity of ovarian cancer diagnosis to 100 % and 86.1 %, respectively (Zhu et al., 2022[162]).