HAND2-AS1 is a downregulated lncRNA in ovarian cancer tissues and cisplatin-resistant ovarian cancer cells, and its ectopic expression stimulates apoptosis, increases BAX protein expression, and decreases BCL-2 protein expression via regulating miR-106a-5p expression in cisplatin-resistant ovarian cancer cells (Li et al., 2021[64]). This evidence concerns the gene HAND2 and ovarian cancer.