Biamonte et al. have shown that let-7g is downregulated in ovarian cancer tissues compared to non-tumoral tissues, and let-7g serum level is decreased in chemoresistant patients compared to chemosensitive ones; let-7g ectopic expression considerably downregulates cyclin D2 expression, arrests the cell cycle, and enhances the chemosensitivity of ovarian cancer cells to cisplatin (Biamonte et al., 2019[10]). This evidence concerns the gene CCND2 and ovarian carcinoma.