In recent years, the research results of RBM15 in cancer have been remarkable, and it has been found that RBM15 acts as an oncogene in breast cancer (Park et al., 2024[187]), laryngeal cancer (Wang et al., 2021[275]), pancreatic cancer (Dong et al., 2023[49]), bladder cancer (Huang et al., 2024[95]), esophageal squamous carcinoma (Wang, 2024[245]), renal clear cell carcinoma (Zeng et al., 2022[330]), cervical cancer (Song and Wu, 2023[216]), and ovarian cancer (Yuan et al., 2023[326]). The gene discussed is RBM15; the disease is clear cell renal carcinoma.