Furthermore, we found that among the m6A readers, the IGF2BPs family was closely associated with pro-tumor progression in lung cancer (Sun et al., 2023[220]; Zhou et al., 2024[370]; Lin et al., 2023[147]), while YTHDC1/2 was a suppressor gene of lung cancer progression (Yuan et al., 2023[327]; Sun et al., 2020[223]), and may become therapeutic targets for lung cancer. This evidence concerns the gene YTHDC1 and lung cancer.