Compared to non-severe adult COVID-19 patients, severe adult patients exhibited dramatically increased secretion of Th1 proinflammatory cytokines, in particular, IL-1β (40.79 vs. 207.84), IL-6 (112.90 vs. 304.15), and IL-8 (1454.66 vs. 2829.79, p = 0.001) in BALF (Supplementary Table S3). The gene discussed is CXCL8; the disease is COVID-19.