Research on lncRNA HEIH in hepatocellular carcinoma has been extensive, and it is recognized as an independent prognostic factor. Moreover, it is hypothesized that HEIH may interact with EZH2, potentially modulating the cell cycle (Bill et al., 2019). Currently, there are limited studies on the correlation between lncRNA HEIH and AML. Ma Yue et al. propose that its overexpression may influence the chemoresistance of AML, thereby affecting the prognosis of AML (Ma and Li, 2024). The gene discussed is EZH2; the disease is hepatocellular carcinoma.