Interleukin-6 (IL-6) stands as a pivotalcytokine orchestratingdiverse physiological processes, ranging from immune responses andinflammation to hematopoiesis.1−3 While crucial for maintaininghomeostasis, aberrant IL-6 expression is implicated in a wide spectrumof diseases, including autoimmune disorders, chronic inflammatoryconditions, cancer, and the life-threatening cytokine storm observedin severe infections like COVID-19.4−7 Understanding the mechanisms underlyingIL-6 induction and developing targeted therapeutic interventions areessential for addressing these health challenges. The gene discussed is IL6; the disease is cancer.