However,while IL-6 plays a critical role in immune responses, it is also implicatedin the pathogenesis of various diseases, including the cytokine stormassociated with severe infections.11 Therefore,precise identification of IL-6 epitopes, with an understanding oftheir induction levels, is crucial for the safe and effective designof epitope-based vaccines and immunotherapies. The gene discussed is IL6; the disease is infection.