Finally, we performed classification-regression tree (CART) analysis of the 8 cytokines/chemokines (IL-10, CCL4, TGFα, IL-12p40, IL-13, CXCL1, CCL22, and IL-17A) and 4 orignial clinical phenotypes (diabetes, dialysis, metastatic infection, and cardiac vegetation) in our training cohort to determine clinically relevant analyte thresholds that could correctly discriminate a later APMB outcome at presentation of MRSA bacteremia. Here, CCL4 is linked to diabetes mellitus.