Of interest, common variants in the SVIL locus are also associated with dilated cardiomyopathy (DCM)3 and, using a Bayesian pairwise analysis approach (GWAS-PW33) including the present HCM GWAS meta-analysis and a published DCM GWAS34, we show that DCM and HCM share the same causal SNP but with the expected opposite directions of effect (Supplementary Table 20). This evidence concerns the gene SVIL and familial dilated cardiomyopathy.