MYC and neoplasm: Specifically, loss of this cluster in mice exhibited reduced B cell apoptosis leading to increased numbers of total B cells in peripheral blood, bone marrow, and spleen [88], whereas enforced expression of miR-132 within the Eμ-Myc mouse-derived haematopoietic stem and progenitor cells limited the development of B-cell cancers [88], a finding that is consistent with other reports demonstrating tumour-suppressive properties of this miRNA [89, 90].