In recent years, significant progress has been made in the study of anti-neuronal antibodies, such as anti-N-methyl-D-aspartate receptor (anti-NMDAR) and anti-leucine-rich glioma-inactivated 1 (anti-LGI1) antibodies, which have been confirmed as pathogenic antibodies for autoimmune encephalitis.3 The gene discussed is LGI1; the disease is autoimmune encephalitis.