Investigating their relevance in human colorectal cancer tumor and non-tumor tissues, immunoblotting revealed that increased LEDGF/p75 expression (significant increased expression in 9/15, 60.0%) correlated with elevated UBC13 levels in tumor samples (6/6, 100%) (Figure 1(A)–(C)). The gene discussed is UBE2N; the disease is colorectal cancer.