CD4 and pneumococcal pneumonia: This contrasts with our studies using the same approach and lungs recovered from pneumococcal pneumonia, in which RORγt+ TH17 TRM cells are abundant.69 As in prior studies,69 the blood (ivCD45.2+) CD4+ T cell subset distributions and surface marker phenotypes differed from the lungs; the blood also lacked RORγt+ cells in the LH mice (Figures S6A–S6D).