Additionally, other studies have reported that levels of IFN‐γ are elevated during thrombosis,[37] and Th1 and Th17 cells are increased in patients with SLE,[38] or chronic immune thrombocytopenia.[39] These studies are consistent with our observation that the patients in Cluster 2 are mostly female thrombotic APS, with the highest incidence of secondary APS and thrombocytopenia and the highest number of IFN‐γ producing Th1 cells and IL‐17 producing Th17 cells. This evidence concerns the gene IFNG and Venous thrombosis.