Consistent with these previous reports on pathology, the results of spatial stratification (Output 4) analysis, which showed an overrepresentation of CD68 and PECAM1 (CD31) within the spatial domain of the invasive tumor (Figs 5 and S6), demonstrated the infiltration of macrophages and endothelial cells into malignant cancer. The gene discussed is PECAM1; the disease is neoplasm.