CD4 and mitochondrial DNA depletion syndrome 4a: In the multivariable Poisson regression model assessing factors associated with AHD among ART-experienced patients adjusted for clustering at facility level and other baseline characteristics, men were more likely to present with CD4 count < 200 cells/μL during ART (RR 1.63; 95% CI 1.46–1.82) compared to women.