Several recent studies showed that the high expression of various gene encoding immune-related MRs that are known to be important components of anti-tumor immune response, e.g., interferon gamma receptor (IFNGR2) [77], [78], [79], and pattern recognition receptors NOD1 and NOD2 [80], was associated with GBM progression and lower survival. The gene discussed is NOD1; the disease is glioblastoma.