PTEN and neoplasm: Another tumor suppressor miRNA, miR-34a, targets oncogenes including MYC and Bcl-2-Associated X Protein(Bax) (36).In contrast, oncogenic miRNAs, such as miR-21, target tumor suppressor genes like Phosphatase and Tensin Homolog (PTEN) and Programmed Cell Death 4 (PDCD4).