TP53 and neoplasm: According to scientific literature in TP53 Database most breast cancer patients with breast cancer are carriers of non-functional (107/133) or partially functional (21/133) variants, with an average age of tumor manifestation of 39.2 (95% CI: 36.7–41.8) and 48.7 (95% CI: 42.3–55.1) y.o. respectively.