Moderate correlation coefficients (ranging from 0.3 to 0.5) were observed between the expression levels of apelin and KI-67, apelin receptor and KI-67, as well as Furin and KI-67 in primary CRC (Fig. 1I) and their corresponding metastatic liver lesions (Fig. 1J). The gene discussed is FURIN; the disease is colorectal carcinoma.