NUCB1 and neoplasm: The lack of statistically significant differences between in vivo NALM6 tumor control by Hy-CAR-Ts and Nuc-CAR-Ts in NSG mice might be in part due to the fact that NSG mouse neutrophils are present in small numbers, have limited functionality, and are not thought to play a role in a rapidly growing liquid tumor like NALM6 leukemia63.