VPS35 and Parkinson disease: When comparing features of PARK-LRRK2 to other dominantly inherited forms of PD, i.e., PARK-SNCA or PARK-VPS35, it was noticeable that for all analyzed clinical features, SNCA and VPS35 variant carriers had a higher proportion of symptoms reported as present than LRRK2 variant carriers (https://www.mdsgene.org/).