Notably, it was not until the discovery of familial cases that IFP began to be considered a possible tumor rather than a proliferative lesion.[12] Actually, since Schildhaus et al observed that the tumor expressed PDGFRA in a series of 23 IFPs investigation in 2008, there were exons 12, 14, 15, and 18 have been reported in the later IFPs.[13–15] However, as mentioned in the article, there were still many cases with negative PDGFRA gene mutation detection in the literature. The gene discussed is PDGFRA; the disease is neoplasm.