ITGB2 and neoplasm: Liu et al found that the ITGB2-AS1 could up-regulate ITGB2 to enhance the migration and invasion of breast cancer cell.[35] In triple negative breast cancer, ITGB2 overexpression was correlated with the tumor stage and metastasis.[36] In the present study, the expression of ITGB2 was not observably correlated with age and TNM classification in SCLC.