Some AIC cases, such as N-methyl-D-aspartate-associated encephalitis, can also coincide with EBV.[12] However, we were unable to make the same inference regarding the underlying mechanism of EBV-related immunopathogenesis in this case of anti-DPPX encephalitis due to the lack of positive EBV IgM in the CSF. Here, CD40LG is linked to viral encephalitis.