FCGR2B and systemic lupus erythematosus: FCGR2B is the only inhibitory Fc receptor and controls many aspects of immune and inflammatory responses.[71] A meta-analysis conducted by Zhu et al evaluated the association between FCGRs polymorphism and the risk of SLE.[72] T They found that the FCGR2B rs1050501 C allele and the FCGR3A rs396991 T allele may be involved in susceptibility and development of SLE.